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 About 10 results found for searched term "Acetyl-CoA Carboxylase" (0.134 seconds)

Cat.No.  Name Target
M3149 CP 640186 Acetyl-CoA Carboxylase
CP-640186 is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.
M5536 CP-640186 HCl Acetyl-CoA Carboxylase
CP-640186 Hcl is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively; with improved metabolic stability vs CP-610431.
M6137 PF-05175157 Acetyl-CoA Carboxylase
PF-05175157 (Compound 9) is a potent Acetyl-CoA carboxylase (ACC1) inhibitor with IC50s of 23.5±1.1 nM (rat) and 27.0±2.7 nM (human).
M8184 S-2E Acetyl-CoA Carboxylase
S2E
S-2E is an orally active and noncompetitive HMG-CoA reductase and acetyl-CoA carboxylase inhibitor. S-2E has an anti-hyperlipidemic action.
M10670 Acetyl Coenzyme A trisodium Enzymes & Coenzymes
Acetyl coenzyme A sodium salt; Acetyl-CoA trisodium
Acetyl Coenzyme A trisodium (Acetyl-CoA trisodium) is a central metabolic intermediate. Acetyl Coenzyme A trisodium is the actual molecule through which glycolytic pyruvate enters the tricarboxylic acid (TCA) cycle, is a key precursor of lipid synthesis, and is the sole donor of the acetyl groups for acetylation. Acetyl Coenzyme A trisodium acts as a potent allosteric activator of pyruvate carboxylase (PC).
M14290 MK-4074 Acetyl-CoA Carboxylase
MK-4074 is a liver-specific inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 with IC50 values of approximately 3 nM.
M21286 PF-05221304 Acetyl-CoA Carboxylase
Clesacostat
PF-05221304 is an orally bioavailable, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), an enzyme that catalyzes the first step of adipogenesis ab initio (DNL).
M21697 CMS-121 Acetyl-CoA Carboxylase
CMS121
CMS-121 is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage with EC50 values of 7 nM and 200 nM, respectively.
M30850 A-908292  Acetyl-CoA Carboxylase
A-908292 is a potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor, with an IC50 of 38 nM. A-908292 can be used for the research of fatty acid metabolism.
M31105 BAY-3827 AMPK
BAY3827
BAY-3827 is a potent AMPK inhibitor which inhibits AMPK kinase activity with IC50 values of 1.4 nM at low (10 µM ATP concentration) and 15 nM at high (2 mM ATP concentration). BAY-3827 prevents phosphorylation of acetyl-CoA carboxylase 1 (ACC1).



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